Discovering How DNA Binding Sites Control Plant Growth

Have you ever wondered how plants know when and where to grow certain structures? In our lab, we study how proteins called transcription factors turn genes on and off by binding to specific spots in DNA, like a control dial. These regulators can change how plants build their cell walls, which give them strength, help them stand tall, and protect them from stress.

Some plant cells make an extra-strong secondary cell wall, rich in cellulose, hemicellulose, and lignin. This wall is especially important in tissues like xylem, which transports water, and fibers, which add strength. Our research focuses on figuring out how the exact location of a transcription factor’s binding site affects which genes turn on, and in which cells.

As part of our team, you’ll learn and use:

Molecular biology techniques to study DNA and gene expression

Microscopy & imaging to see how plant cells develop

Histology to visualize plant tissues

No prior research experience is required, just curiosity, reliability, and an interest in how living things work. You’ll gain hands-on lab skills, learn how scientists ask and answer questions, and contribute to real scientific discoveries.

Name of research group, project, or lab
Plant Regulatory Genomics Lab
Why participate in this opportunity?

Our mission in the lab is to learn from the scientific method and to train scientists. We work in groups and encourage independence. Be a part of our team and learn how to be a scientist. The Hazen Lab has successfully mentored approximately 60 undergraduate research assistants, transforming them into active contributors in science. Upon joining the lab, you'll assume the role of a working scientist. Our track record reflects the effective training of a diverse cohort of undergraduates, with around half pursuing graduate degrees and the remainder securing positions in the science industry, primarily within the Boston area.

 

Logistics Information:
Subject Category
Genetics
Genomics
Plant Biology
Student ranks applicable
Freshman
Sophomore
Junior
Student qualifications

Freshman and Sophomore Biology, BMB, Microbiology, and Plant and Soil Science majors. Applicants should be excited about being a scientist. It's important to note that the lab may not be the ideal fit for students aiming for medical professional degrees such as MD, DDS, or RN.

Time commitment
5-7 h/wk
8-10 h/wk
11-14 h/wk
Position Types and Compensation
Research - Independent Study or Research Assistant credit
Research - Volunteer
Number of openings
2
Techniques learned

Students will learn molecular techniques such as nucleic acid extraction, PCR, cloning, genetic transformation, and tissue culture. Caring for plants, collecting experimental material, preparing solutions, and cleaning glassware are common activities. You will also learn to do histology and microscopy.

Project start
Fall 2025
Contact Information:
Mentor
hazensam@umass.edu
Principal Investigator
Name of project director or principal investigator
Sam Hazen
Email address of project director or principal investigator
hazensam@umass.edu
2 sp. | 7 appl.
Hours
5-7 h/wk (+2)
5-7 h/wk8-10 h/wk11-14 h/wk
Project categories
Genomics (+2)
GeneticsGenomicsPlant Biology