Research about how sea slugs process smells

This project investigates the organization of a sea slug brain using modern molecular and computational tools, focusing on the sense of smell (olfaction). The goal is to understand how the rhinophore (the slug equivalent of a nose) works in the nudibranch, Berghia stephanieae. We will employ a combination bioinformatic approaches and molecular techniques including single-cell RNA sequencing to:  identify, describe, and classify the genes that code for receptor proteins involved in olfaction and then localize their expression to neurons.

It is often assumed that processing the multitude of signals that an animal receives from its environment happens in the brain (or central nervous system, CNS) rather than in the nerves outside the brain (peripheral nervous system, PNS). However, we have evidence that suggests that sea slugs begin to process olfactory information in the PNS of their rhinophores. Understanding whether the PNS in molluscs performs functions that we usually think are reserved for the CNS could change how we think about what the brain actually does.

Ideally, you will be assisting us with all stages of the project. Training will be provided. You should be comfortable working both at the bench in the lab and with computers. Some of the protocols involved demand careful attention to detail over long periods of time. 

Please indicate in your essay: i) why are you interested in this opportunity and what stands out to you the most; ii) examples of projects or tasks that you have been involved with, which required a long-term commitment and attention to detail; iii) a brief description of how this opportunity would assist you in your career goals.