Developing hydrogel systems for brain organoid culture

The Sun lab is seeking a motivated and detail-oriented undergraduate student to contribute to a research project focused on the synthesis and characterization of hyaluronic acid–based hydrogels for brain organoid development. This work aims to design biomaterial systems that better mimic the brain microenvironment.


The student will assist with polymer functionalization, hydrogel synthesis, and physicochemical characterization. Techniques may include pH adjustment, lyophilization, nuclear magnetic resonance (NMR) spectroscopy, and rheological analysis of hydrogel mechanical properties. Emphasis will be placed on careful experimental work, good record-keeping, and reproducibility.


There may also be limited opportunities to support organoid culture and imaging, where microscopy is used to assess organoid development.
 

 

 


 

Name of research group, project, or lab
Laboratory for Multiscale Bioengineering and Mechanobiology
Why participate in this opportunity?

This position is a good fit for students looking to gain hands-on research experience and build technical skills in an interdisciplinary lab environment.

 

Representative publication or further information
Logistics Information:
Field(s) of Study
Biology
Biomedical Engineering
Chemical Engineering
Chemistry
Mechanical & Industrial Engineering
Student ranks applicable
Sophomore
Junior
Student qualifications

Preferred qualifications:
• Some prior wet lab experience (course-based or research) 
• Strong attention to detail and willingness to learn new techniques 
• Ability to commit consistently (through independent study or honor thesis)
• Interest in biomaterials, bioengineering, or related fields

Time commitment
8-10 h/wk
11-14 h/wk
15+ h/wk
Position Types and Compensation
Credit for Research and Teaching
Unpaid - Volunteer
Number of openings
1
Techniques learned

Techniques may include pH adjustment, lyophilization, nuclear magnetic resonance (NMR) spectroscopy, and rheological analysis of hydrogel mechanical properties. 

There may also be limited opportunities to support organoid culture and imaging, where microscopy is used to assess organoid development.

Project start
start immediately.
Contact Information:
Mentors
ybsun@umass.edu
Associate Professor
feiyangchen@umass.edu
Postdoctoral associate
Name of project director or principal investigator
Yubing Sun
Email address of project director or principal investigator
ybsun@umass.edu
1 sp. | 0 appl.
Time commitment
8-10 h/wk (+2)
8-10 h/wk11-14 h/wk15+ h/wk
Field(s) of Study
Mechanical & Industrial Engineering (+4)
BiologyBiomedical EngineeringChemical EngineeringChemistryMechanical & Industrial Engineering